This may not sound like a challenge to Gutenberg and print, but it will definitely reduce the importance of traditional publishers. Amazon still acknowledge the fact that some people prefer to read printed books, so we have the CreateSpace, which makes it very easy to upload your finished manuscript and have that script in the CreateSpace print paperback form.
Of course, Amazon has gone one step further and allow authors to upload their book to the Kindle format (which, incidentally, is also available on the iPad). Thus we have an author who has the option to go directly to the issuing, publishing, e-books in print or both. If the author decides to publish the manuscript/in print and e-book, he must then upload to the CreateSpace direct Publishing, and the Kindle Amazon company. In my experience, both formats are relatively easy to use.